Target therapy in metastatic renal cell carcinoma
نویسندگان
چکیده
منابع مشابه
Sequential Therapy in Metastatic Renal Cell Carcinoma
The treatment of metastatic renal cell carcinoma (mRCC) has changed dramatically in the past decade. As the number of available agents, and related volume of research, has grown, it is increasingly complex to know how to optimally treat patients. The authors are practicing medical oncologists at the US Oncology Network, the largest community-based network of oncology providers in the country, a...
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Introduction: Metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. The most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. Renal cell carcinoma accounts for nearly 3% of all adult malignancies. It usually metastasizes to the lungs,...
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Efficacy of new molecularly targeted drugs in the treatment of renal cell carcinoma (RCC), confirmed in clinical studies in relation to survival and prolongation of time to progression, has became a big chance for patients with metastatic renal cell cancer. Axitinib is a potent and selective receptor tyrosine kinase for vascular endothelial growth factor (VEGFR-1, -2, -3), platelet-derived grow...
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BE At the 2007 American Society of Clinical Oncology meeting, Merchan and colleagues presented results from the phase I portion of a trial that aimed to determine the maximum tolerated dose and dose-limiting toxicity of the combination of the mammalian target of rapamycin (mTOR) inhibitor temsirolimus (Torisel, Pfizer) and the anti-vascular endothelial growth factor (VEGF) monoclonal antibody b...
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ژورنال
عنوان ژورنال: European Journal of Cancer Supplements
سال: 2008
ISSN: 1359-6349
DOI: 10.1016/j.ejcsup.2008.06.022